|
KMID : 0191120000150050585
|
|
Journal of Korean Medical Science
2000 Volume.15 No. 5 p.585 ~ p.588
|
|
|
Churg-Strauss syndrome with perforating ulcers of the colon
|
|
Kim YB
Choi SW/Park IS/Han JY/Hur YS/Chu YC
|
|
|
Abstract
|
|
|
We report a case of a 72-year-old woman with Churg-Strauss syndrome, who presented with intestinal
perforation. She has had bronchial asthma with peripheral blood eosinophilia for 30 years. Gross
findings of a resected colon showed multiple ulcers with perforation. Histologic findings demonstrated
transmural inflammation infiltrated with large numbers of eosionophils, neutrophils and lymphoplasma
cells, and characteristic extravascular granuloma in the subserosa. There were multifocally-distributed
transmural vasculitis showing all stages of activity in medium and small-sized arteries and veins located
in the submucosa, and proper muscle and subserosal layers of the colon, some of which revealed
granulomatous inflammation. Histologic finding of liver showed chronic viral hepatitis B with mild
inflammatory activity and macronodular cirrhosis. Immunohistochemical findings, acid fuschin orange
G staining and electromicroscope found no evidence of hepatitis B virus infection contributing to
the pathogenesis of this lesion.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|